my mouse has 2 extra buttons on the side, I bind one to regular click and another to self casting (which I rarely use, I plan on trying it with the Attack Champions Only keybind once i stop being a shitter)
in general I probably would not recommend it if you are adept at using the A button to attack move, the tradeoff is that it teaches some really bad habits that I still haven't unlearned (fighting in lanes and hitting minions by mistake, cs mistakes, etc) but it's still pretty good if you want to take the time to make the transition. left clicking is generally not that useful unless you are clicking another champion (after enough games cs'ing becomes automatic so you probably will never have to click minions) or you're in base. having it in a slightly less convenient spot is fine by me. it also messes with regular cast so you have to be a 100% smartcast player basically or else you'll screw yourself
iirc you cannot technically rebind left click (or anything to left click) if you have a non-programmable mouse unless you mess with the game files, which could slightly mess with some other bindings (like pressing a button to left click). also I'm pretty sure you can rebind it to the mouse wheel click if you're braver than I am
in general I probably would not recommend it if you are adept at using the A button to attack move, the tradeoff is that it teaches some really bad habits that I still haven't unlearned (fighting in lanes and hitting minions by mistake, cs mistakes, etc) but it's still pretty good if you want to take the time to make the transition. left clicking is generally not that useful unless you are clicking another champion (after enough games cs'ing becomes automatic so you probably will never have to click minions) or you're in base. having it in a slightly less convenient spot is fine by me. it also messes with regular cast so you have to be a 100% smartcast player basically or else you'll screw yourself
iirc you cannot technically rebind left click (or anything to left click) if you have a non-programmable mouse unless you mess with the game files, which could slightly mess with some other bindings (like pressing a button to left click). also I'm pretty sure you can rebind it to the mouse wheel click if you're braver than I am