A frickin’ awesome "Anti-Lead" that I find is almost always getting me off to a good start.
http://www.smogon.com/dp/pokemon/grumpig
[SET]
Name: Anti-Lead (UU)
Move 1: Magic Coat
Move 2: Psychic
Move 3: Hidden Power Bug / Hidden Power Ice
Move 4: Reflect / Thunder Wave
Item: Expert Belt
EVs: 140 HP / 100 Def / 252 SAtk / 16 SDef
Nature: Modest
Ability: Thick Fat
[SET COMMENTS]
<p>Grumpig can work as a lead in UU to get your team off to a good start. Magic Coat means status gets bounced back, and can immediately stop the likes of Persian and Venomoth who may try to sleep you, while you then Reflect, or predict a switch and Thunder Wave. To give you an idea of its defensive capabilities, it also survives Jolly Choice Band Primeape’s U-Turn while it can OHKO Primeape with Psychic. The EV spread also gives you a 46% chance to OHKO standard Rapid Spin Hitmontop, who can only really Toxic you for damage, which can be reflected back through Magic Coat.</p>
<p>Hidden Power Bug is used for darks, namely Absol, who you have a 20% chance to OHKO, although Hidden Power Ice can be used to hit Altaria and Leafeon harder. Reflect is used to buffer hits and for team support, while Thunder Wave can paralyze threats who think they are switching in easily. Counter is an option to help against Persian and Primape, who's U-Turn's will not OHKO, so you can hit the switch-in hard, for a possible KO.</p>
http://www.smogon.com/dp/pokemon/grumpig
[SET]
Name: Anti-Lead (UU)
Move 1: Magic Coat
Move 2: Psychic
Move 3: Hidden Power Bug / Hidden Power Ice
Move 4: Reflect / Thunder Wave
Item: Expert Belt
EVs: 140 HP / 100 Def / 252 SAtk / 16 SDef
Nature: Modest
Ability: Thick Fat
[SET COMMENTS]
<p>Grumpig can work as a lead in UU to get your team off to a good start. Magic Coat means status gets bounced back, and can immediately stop the likes of Persian and Venomoth who may try to sleep you, while you then Reflect, or predict a switch and Thunder Wave. To give you an idea of its defensive capabilities, it also survives Jolly Choice Band Primeape’s U-Turn while it can OHKO Primeape with Psychic. The EV spread also gives you a 46% chance to OHKO standard Rapid Spin Hitmontop, who can only really Toxic you for damage, which can be reflected back through Magic Coat.</p>
<p>Hidden Power Bug is used for darks, namely Absol, who you have a 20% chance to OHKO, although Hidden Power Ice can be used to hit Altaria and Leafeon harder. Reflect is used to buffer hits and for team support, while Thunder Wave can paralyze threats who think they are switching in easily. Counter is an option to help against Persian and Primape, who's U-Turn's will not OHKO, so you can hit the switch-in hard, for a possible KO.</p>