Common Roles

Defensive Utility: Wish, Thunder Wave, and Knock Off give Wigglytuff the tools to act as a support Pokemon and cleric for its teammates, especially during matchups against weaker offensive Pokemon, or Ghost- and Dragon-types. Wigglytuff is typically used in this role to disrupt the opponent’s offense and setup sweepers and provide opportunities for its teammates to take advantage of.

Common Moves

Primary STAB Moves: Alluring Voice, Hyper Voice, Play Rough, Body Slam

Setup Moves: Nasty Plot, Calm Mind

Utility Moves: Knock Off, Stealth Rock, Wish, Thunder Wave, Taunt, Encore, Disable, Reflect, Light Screen, Brick Break, Protect, Psychic Noise

Coverage: Flamethrower, Fire Blast, Thunderbolt, Ice Beam, Energy Ball, Focus Blast, Psychic, Psyshock, Shadow Ball

Niche Moves

Misty Explosion: Misty Explosion can be used on lead Wigglytuff movesets in order to deal respectable damage and bring in a teammate safely to pick off the opponent.

Perish Song: In an emergency situation, Perish Song can be used to put a time limit on a particularly threatening foe, such as a Dragon Dance sweeper or bulky Calm Mind user.

Common Items

Leftovers: Leftovers improves Wigglytuff’s longevity, allowing it to live hits more easily, disrupt foes, and more frequently heal teammates with Wish.

Heavy-Duty Boots: Heavy-Duty Boots allows Wigglytuff to switch in more easily against teams with strong entry hazard-setting, preventing it from taking large chip damage from Stealth Rock, Spikes, and poison via Toxic Spikes, which can be a severe detriment to Wigglytuff's longevity.

Niche Items

Light Clay: Used on movesets with Reflect and Light Screen, Light Clay allows Wigglytuff to reduce incoming damage towards its teammates for a longer time.

Mental Herb: Mental Herb can be used as a one-time nullification of Taunt or Encore, guaranteeing Wigglytuff that it can use Stealth Rock or Thunder Wave.

Rocky Helmet: Wigglytuff's passable bulk allows it to switch in on physical attackers, using Rocky Helmet to inflict damage against foes with contact moves and punish foes with pivoting moves such as U-turn.

Tera

Wigglytuff should not be drafted as a Tera Captain due to its subpar bulk and offensive stats. If Wigglytuff is made a secondary Tera Captain, Tera Fairy can be used to allow Wigglytuff to check Fighting-types and bolster its Alluring Voice. Alternatively, Tera Fire can let it function as a lure versus Steel-types, resisting their super effective coverage and hitting them back with a boosted Flamethrower or Fire Blast.

Draft Strategy

Wigglytuff should only be considered as a very niche pick for the main purpose of helping teams that struggle with Ghost-, Dragon-, and Dark-types. Using its large utility movepool for disruption, Wigglytuff can act as a decent check to these Pokemon, but it should not be the only Pokemon on a team to cover these roles.

Offensive Threats: Disruption utility in the form of Thunder Wave provided by Wigglytuff is enjoyed by offensive threats such as Darkrai, Tornadus-T, and Enamorus, which in particular appreciate speed control and can find more opportunities to wallbreak or set up. Wigglytuff’s ability to be a blanket check to Ghost- and Dark-types means that it can take the pressure off of Psychic-type attackers by sponging incoming Ghost- and Dark-type moves decently well. Latios and Deoxys-S therefore appreciate Wigglytuff’s typing and support capabilities moreso than others.

Entry Hazard Setters: Wigglytuff is a Stealth Rock setter, and while it might not be reliable in an extended match, it can alleviate pressure from other Stealth Rock setters such as Great Tusk, Iron Treads, and Landorus-T and allow them to run more offensive movesets if they're required.

Checks and Counters

Taunt / Encore: Wigglytuff is highly reliant on status moves to provide support for its teammates, so Taunt from the likes of Ogerpon and Tornadus-T can completely disrupt Wigglytuff and allow for free turns of setup if Wigglytuff is not running disruption itself in the form of Alluring Voice. Encore from Annihilape, Iron Valiant, and Iron Bundle can completely shut down Wigglytuff and allow for free turns of setup or damage.

Steel- and Fire-types: While Wigglytuff carries coverage for Steel-types, many such as Gholdengo, Iron Treads, and Iron Crown are faster and either strong enough to OHKO Wigglytuff or bulky enough to shrug off non-STAB Flamethrower or Fire Blast. Wigglytuff does not carry any meaningful offensive coverage for most Fire-types and so struggles to deal significant damage. Heatran, Cinderace, and Chi-Yu can therefore reliably handle Wigglytuff with Taunt or strong offensive coverage and STAB Fire-type moves.

Strong Wallbreakers: Naturally strong wallbreakers like Gouging Fire, Ursaluna, and Thundurus-T may overwhelm Wigglytuff's bulk and push past its Wish + Protect strategy. Due to the predictability of this set, setup sweepers can use the turns that Wigglytuff uses Protect to boost their offenses with Dragon Dance, Swords Dance, or Nasty Plot. Most of these Pokemon do need to fear its Thunder Wave, however.