Clefairy offers incredible utility, giving teams a sturdy Knock Off user that can also establish Stealth Rock and disrupt foes with Thunder Wave, all valuable tools that help against the premier entry hazard removal option in the tier, Quaxwell. Encore can similarly disrupt the opponent, though it is prediction-reliant, as most things will be faster than Clefairy without being paralyzed. Night Shade can be used to provide consistent damage output, though it can't hit Dunsparce, Girafarig, and Vigoroth, giving them opportunities to set up in front of Clefairy. Magic Guard allows Clefairy to sponge status moves and other forms of residual damage for its teammates, such as Toxic from Dunsparce, Salt Cure from Naclstack, and Will-O-Wisp from Misdreavus, though it does still suffer the effects of paralysis and takes boosted damage from Hex while statused. A specially defensive EV spread with a Calm nature lets Clefairy focus on checking Pokemon like Drakloak, Frogadier, and Misdreavus, while a physically defensive EV spread with a Bold nature can let it check Monferno and Piloswine.

A natural fit on balance and bulky offense teams, Clefairy can use its utility to free up a moveslot on teammates like Dunsparce, Gabite, Misdreavus, and Piloswine. Clefairy uses its bulk and general longevity to disrupt the opposition drastically, allowing offensive teammates, like Frogadier and Girafarig, to clean late-game after Eviolites are removed from walls such as Dunsparce, Misdreavus, and Tinkatuff. Teammates that appreciate the paralysis spread by Clefairy include Hex users like Drakloak and Misdreavus, which can use the boosted damage to break through special walls like opposing Clefairy and Tinkatuff. Frogadier is a notable partner for Clefairy, as it uses Spikes to create an entry hazard-stacking core that, with Misdreavus as a spinblocker, can rack up hazard chip damage. While Clefairy is fairly bulky and can use Moonlight to stick around for longer, it is generally frail once its Eviolite is removed and can struggle to wall the stronger setup sweepers and wallbreakers in the tier, such as Nasty Plot Girafarig, Contrary + Leaf Storm Servine, and Swords Dance Thwackey. To help with this, Hisuian Sliggoo can cover a lot of these threats because of its own bulk and Steel typing, and it can capitalize on Clefairy removing Eviolites on foes to maximize the damage output of its own strong STAB attacks like Draco Meteor and Flash Cannon. Koffing and Pawniard can also help sponge Knock Offs for Clefairy, with Koffing providing great offensive pressure with Toxic Spikes and Pawniard being a reliable wallbreaker. Fighting-types like Pignite can help Clefairy break through the bulkier Normal- and Steel-types that it can struggle against, like Dunsparce and Hisuian Sliggoo. Gabite can similarly help break through these Pokemon while also threatening Koffing and other Poison-types like Glimmet.